Swoboda W, Bohrn E
Wien Med Wochenschr. 1981 Mar 15;131(5):127-32.
Report on the successful treatment of pubertal gynecomastia with the synthetic steroid preparation Danazol. In 15 male adolescents, 11 to 18 years old, Danazol in an average dose of 8 to 10 mg/kg/day, administered orally over 2 to 3 months, achieved a very good or good reduction of breast tissue. 4 patients showed a palpable but insufficient regression. Side-effects of the treatment were rare and clinically negligible. The mechanism of the hormonal action of the gonadotropin inhibiting steroid Danazol in gynecomastia cannot be explained by the hormone findings available so far.
关于合成类固醇制剂达那唑成功治疗青春期男性乳腺增生症的报告。在15名年龄在11至18岁的男性青少年中，以平均8至10毫克/千克/天的剂量口服达那唑2至3个月，乳腺组织得到了非常好或良好的缩减。4名患者的乳腺组织有可触及的缩小，但程度不足。治疗的副作用罕见，临床上可忽略不计。促性腺激素抑制类固醇达那唑在男性乳腺增生症中的激素作用机制无法用目前已知的激素研究结果来解释。
