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Radiology. 1976 Jan;118(1):219-23. doi: 10.1148/118.1.219.
The early demonstration of immunologic specificity of antibodies and the discovery of tumor antigenic specificity are reviewed in the light of experimental and clinical attempts to use such reagents in the management of cancer. Recent results in regard to tumor antigens and radiolabeled antibody preparations are shown to be practical for experimental diagnosis and therapy and potentially for similar clinical purposes.
鉴于在癌症治疗中使用此类试剂的实验和临床尝试,本文回顾了抗体免疫特异性的早期证明以及肿瘤抗原特异性的发现。关于肿瘤抗原和放射性标记抗体制剂的最新结果表明,它们在实验诊断和治疗中具有实用性,并且在潜在的临床应用中也可能具有相似的用途。