磷脂膜的电容
The electrical capacitance of phospholipid membranes.
作者信息
Ohki S
出版信息
Biophys J. 1969 Oct;9(10):1195-205. doi: 10.1016/S0006-3495(69)86445-3.
Abstract
As one of the methods of finding out the structural change of lipid bilayers due to change of environmental solution, the capacitances of phosphatidyl choline (egg lecithin) and phosphatidyl serine (bovine brain) bilayer membranes in solutions of various pH and salt contents were measured. It was found that the capacitance of the bilayer depended upon pH and salt content. The capacitance had a minimum value around pH 4 for phosphatidyl choline and around pH 3-4 for phosphatidyl serine bilayers, respectively. The value of the capacitance increased as the pH of the solution became lower or higher. As the concentration of cholesterol in the phosphatidyl choline bilayer increased, the capacitance increased and reached a saturation value. A DC voltage across the phosphatidyl choline bilayer did not affect the value of the capacitance practically.
摘要
作为探究环境溶液变化导致脂质双层结构变化的方法之一，测量了磷脂酰胆碱（卵磷脂）和磷脂酰丝氨酸（牛脑）双层膜在不同pH值和盐含量溶液中的电容。发现双层膜的电容取决于pH值和盐含量。磷脂酰胆碱双层膜在pH约为4时电容有最小值，磷脂酰丝氨酸双层膜在pH约为3 - 4时电容有最小值。随着溶液pH值变低或变高，电容值会增加。随着磷脂酰胆碱双层膜中胆固醇浓度的增加，电容增大并达到饱和值。磷脂酰胆碱双层膜上的直流电压实际上并不影响电容值。
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