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恒河猴淋巴细胞同种抗原。III. 新抗原的鉴定。

Rhesus lymphocyte alloantigens. III. Identification of new antigens.

作者信息

Neefe J R, Ellis E B, Rogentine G N

出版信息

Tissue Antigens. 1975 Oct;6(4):195-204. doi: 10.1111/j.1399-0039.1975.tb00634.x.

Abstract

Rhesus monkey lymphocytotoxic alloantisera were tested in 437 random unrelated monkeys and in members of 19 pedigreed families. Groups of sera or individual sera identified 11 specificities. Genetic analysis of the associations of these antigens revealed behavior consistent with the current concept of the major histocompatibility complex of several mammalian species including man in that the antigens could be grouped into two series of closely linked co-dominantly expressed alleles.

摘要

在437只随机选取的无亲缘关系的猴子以及19个谱系家族的成员中对恒河猴淋巴细胞毒性同种抗血清进行了检测。血清组或单个血清识别出了11种特异性。对这些抗原关联的遗传分析显示,其行为与包括人类在内的几种哺乳动物主要组织相容性复合体的当前概念一致,即这些抗原可分为两个紧密连锁的共显性表达等位基因系列。

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