Adamec O, Kosutzký J, Kirchmayerová J
Vet Med (Praha). 1975 Jul;20(7):433-40.
A biological test was performed to study the changes in the effectiveness of androgens after the administration of different doses of lindane to sexually immature cockerels. Testosterone-propionate and Stenolon were used as reference hormones. The results indicate that the administration of lindane increases the biological effectiveness of testosterone-propionate expressed through the stimulation of the growth of comb. On the other hand, the effect of the insecticide caused a statistically highly significant reduction of androgenic activity when Stenolon was used as a reference preparation. The causes leading to different manifestations of the interactions of lindane with the two hormones tested are analyzed. The paper gives further proofs that the exposure of poultry to relatively low doses of chlorinated insecticides interferes with the biological effectiveness of sex hromones.
进行了一项生物学试验，以研究向性未成熟的小公鸡施用不同剂量林丹后雄激素效力的变化。丙酸睾酮和司坦唑醇用作参考激素。结果表明，施用林丹可通过刺激鸡冠生长来提高丙酸睾酮的生物学效力。另一方面，当以司坦唑醇作为参考制剂时，该杀虫剂的作用导致雄激素活性在统计学上显著降低。分析了导致林丹与所测试的两种激素相互作用表现不同的原因。本文进一步证明，家禽接触相对低剂量的氯化杀虫剂会干扰性激素的生物学效力。
