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妊娠贫血对人胎盘细胞生长的影响。

Effect of pregnancy anaemia on cellular growth in the human placenta.

作者信息

Marwah P, Singla P N, Krishna M, Agarwal K N

出版信息

Acta Paediatr Scand. 1979 Nov;68(6):899-901. doi: 10.1111/j.1651-2227.1979.tb08230.x.

DOI:10.1111/j.1651-2227.1979.tb08230.x
PMID:539413
Abstract

The effects of pregnancy anaemia on cell number and size in human placentae were investigated. Total organ weight, protein, RNA and DNA contents were determined in 54 fresh placentae from anaemic women (haemoglobin less than 110 g/l) and another 32 placentae from women without anaemia (haemoglobin greater than or equal to 110 g/l). The placental weight was significantly reduced in pregnancy anaemia. The decrease in total placental DNA in anaemic women suggested that the reduced placental weight was due to a decrease in cell number. However, these placentae also showed evidence of compensatory cellular hypertrophy as indicated by increase in both weight per cell and protein per cell.

摘要

研究了妊娠贫血对人胎盘细胞数量和大小的影响。测定了54例贫血妇女(血红蛋白低于110 g/l)新鲜胎盘以及另外32例非贫血妇女(血红蛋白大于或等于110 g/l)胎盘的总器官重量、蛋白质、RNA和DNA含量。妊娠贫血时胎盘重量显著降低。贫血妇女胎盘总DNA减少表明胎盘重量减轻是由于细胞数量减少。然而,这些胎盘也显示出代偿性细胞肥大的证据,表现为每细胞重量和每细胞蛋白质增加。

相似文献

1
Effect of pregnancy anaemia on cellular growth in the human placenta.妊娠贫血对人胎盘细胞生长的影响。
Acta Paediatr Scand. 1979 Nov;68(6):899-901. doi: 10.1111/j.1651-2227.1979.tb08230.x.
2
Effect of maternal anaemia on the placenta and the newborn infant.
Acta Paediatr Scand. 1978 Sep;67(5):645-8. doi: 10.1111/j.1651-2227.1978.tb17816.x.
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Placental ratio and anemia in third-trimester pregnancy.孕晚期胎盘比值与贫血
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The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight.母体贫血和缺铁对胎儿体重与胎盘重量之比的影响。
Br J Obstet Gynaecol. 1991 Sep;98(9):886-91. doi: 10.1111/j.1471-0528.1991.tb13510.x.
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Morphological study of placenta in pregnancy anaemia.妊娠贫血时胎盘的形态学研究
Indian J Pathol Microbiol. 1979 Jan;22(1):7-12.
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[Correlation between maternal hemoglobin levels and placental morphology and findings in newborn infants].[母亲血红蛋白水平与胎盘形态及新生儿检查结果之间的相关性]
Z Geburtshilfe Perinatol. 1987 May-Jun;191(3):81-4.
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The effects of anaemia on heart, placenta and body weight, and blood pressure in fetal and neonatal rats.贫血对胎鼠和新生鼠心脏、胎盘、体重及血压的影响。
J Physiol. 1995 Oct 15;488 ( Pt 2)(Pt 2):515-9. doi: 10.1113/jphysiol.1995.sp020986.
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The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight.母亲贫血和缺铁对胎儿体重与胎盘重量之比的影响。
Br J Obstet Gynaecol. 1992 Mar;99(3):271-2. doi: 10.1111/j.1471-0528.1992.tb14520.x.
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[Morphological changes in the mature placenta in anemia in pregnant women].[孕妇贫血时成熟胎盘的形态学变化]
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The water and nitrogen composition of the placenta in anemic women.贫血女性胎盘的水和氮成分
Int J Gynaecol Obstet. 1978;15(5):462-3. doi: 10.1002/j.1879-3479.1977.tb00732.x.

引用本文的文献

1
Maternal and Cord Blood Hemoglobin as Determinants of Placental Weight: A Cross-Sectional Study.母体及脐带血血红蛋白作为胎盘重量的决定因素:一项横断面研究。
J Clin Med. 2021 Mar 2;10(5):997. doi: 10.3390/jcm10050997.
2
Nutrition deprivation: effects on feto-placental unit and fetal brain.营养剥夺:对胎儿-胎盘单位及胎儿大脑的影响
Indian J Pediatr. 1980 Jan-Feb;47(384):19-26. doi: 10.1007/BF02900166.
3
Intravascular volume expansion and fetal outcome in pregnant Nigerians with hemoglobin SS and SC.血红蛋白SS和SC的尼日利亚孕妇的血管内容量扩充与胎儿结局
J Natl Med Assoc. 1988 Aug;80(8):906-12.