Gómez-Estrada H, Acosta-Ruíz R, Ramos-Damian M E, Alpuche-Villanueva J, González-Marmolejo R, Rayón-Rios F
Arch Invest Med (Mex). 1979;10(4):187-200.
Radiosensitivity of L5178/ murine lymphoma was studied in vivo by means of Co60 pump radiations. The dosage necessary to inactivate these cells was from 5,000 to 6,000 rads applied in an only dose. Doses under 2,000 to 4,000 rads only achieved partial inactivation, proportional to dosage applied. 100 to 1600 rad doses did not produce adverse effects on these cells. Lethal dose for carrier mice was from 800 to 1200 rads applied in one dose only or a total of over 600 rads applied in 100 rad daily sessions. High radioresistance of lymphoma did not allow destruction of all neoplastic cells in vivo for, before this occurred carrier mice died.
通过钴60泵浦辐射在体内研究了L5178 /小鼠淋巴瘤的放射敏感性。使这些细胞失活所需的剂量为单次给予5000至6000拉德。2000至4000拉德以下的剂量仅实现部分失活，与所施加的剂量成比例。100至1600拉德的剂量对这些细胞没有产生不利影响。载体小鼠的致死剂量为单次给予800至1200拉德或每天给予100拉德，总共超过600拉德。淋巴瘤的高放射抗性不允许在体内破坏所有肿瘤细胞，因为在此之前载体小鼠死亡。
