[大鼠的针刺镇痛及其在吗啡和纳洛酮作用下的变化]
[Acupuncture analgesia in rats and its changes under the effect of morphine and naloxone].
作者信息
Vasil've Iu N, Kachan A T, Bogdanov N N
出版信息
Biull Eksp Biol Med. 1979 Nov;88(11):556-9.
PMID:540143
Abstract
It was established in chronic experiments on rats that electric acupuncture of the acupuncture point noticeably decreases pain reaction to electric stimulation of the tail. Morphine given in a subanalgetic dose (5 mg/kg) potentiated acupuncture analgesia, while 5 mg/kg of naloxone completely abolished it. Potential mechanisms of analgesia realization during electric acupuncture are discussed.
摘要
在对大鼠的慢性实验中发现，针刺穴位的电针疗法可显著降低对尾部电刺激的疼痛反应。给予亚镇痛剂量（5毫克/千克）的吗啡可增强针刺镇痛效果，而5毫克/千克的纳洛酮则可完全消除这种效果。文中讨论了电针过程中镇痛作用实现的潜在机制。
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