Fischer F
Dtsch Z Verdau Stoffwechselkr. 1979;37(4):189-92.
Follow up studies in 19 diabetic patients with manifestation in the youth. Proteinurie within few years; later on nephropathy: 7 cases with glomerulosclerosis, 8 with arteriolosclerosis, 3 with pyelonephritis and 1 with chronic glomerulonephritis. In all cases retinopathy, very often coronarsclerosis, seldom peripheral and cerebral sclerosis. 14 patients died, mostly in young age in consequence of nephropathy. Proteinurie is a malignant symptom of diabetic angiopathy; in contrast to the retinopathy.
对19例青年期发病的糖尿病患者进行随访研究。数年内出现蛋白尿;随后发展为肾病:7例为肾小球硬化,8例为小动脉硬化,3例为肾盂肾炎,1例为慢性肾小球肾炎。所有病例均有视网膜病变,常伴有冠状动脉硬化,很少有外周血管硬化和脑硬化。14例患者死亡,大多死于青年期,死因是肾病。蛋白尿是糖尿病血管病变的恶性症状;与视网膜病变不同。