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血小板在异丙肾上腺素诱发的大鼠心肌梗死中的作用(作者译)

[The role of the platelets in myocardial infarction induced by isoproterenol in the rat (author's transl)].

作者信息

Cacciapuoti A A, Giuffrida G, Mazza F, Polverino W, Genovese A

出版信息

G Ital Cardiol. 1979;9(7):767-8.

PMID:540709
Abstract

The AA. suggest that the myocardial infarction induced by isoproterenol in the rat may be determined by phenomenons of intracoronaric platelets aggregation. The effects on the degree and extension of the infarctual necrotic area have been evaluated in a drug with remarkable platelets antiaggregation activity (ASL). The following parameters are considered: wet and dry weight of the organ, and tissutal CPK levels.

摘要

作者们认为,异丙肾上腺素在大鼠体内诱发的心肌梗死可能由冠状动脉内血小板聚集现象所决定。已在一种具有显著抗血小板聚集活性的药物(ASL)中评估了其对梗死坏死面积程度和范围的影响。考虑了以下参数:器官的湿重和干重以及组织肌酸磷酸激酶水平。

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