苯乙双胍作用部位及作用机制的研究。II. 苯乙双胍对大鼠肠道葡萄糖转运的抑制作用 - Suppr

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Studies on the site and mechanism of action of phenformin. II. Phenformin inhibition of glucose transport by rat intestine.

作者信息

Kruger F A, Altschuld R A, Hollobaugh S L, Jewett B

出版信息

Diabetes. 1970 Jan;19(1):50-2. doi: 10.2337/diab.19.1.50.

DOI:10.2337/diab.19.1.50

PMID:5410102

Abstract

摘要

相似文献

Studies on the site and mechanism of action of phenformin. II. Phenformin inhibition of glucose transport by rat intestine.苯乙双胍作用部位及作用机制的研究。II. 苯乙双胍对大鼠肠道葡萄糖转运的抑制作用

Diabetes. 1970 Jan;19(1):50-2. doi: 10.2337/diab.19.1.50.

Studies on the site and mechanism of action of phenformin. I. Evidence for significant "nonperipheral" effects of phenformin on glucose metabolism in normal subjects.苯乙双胍作用部位及作用机制的研究。I. 苯乙双胍对正常受试者糖代谢有显著“非外周”效应的证据。

Diabetes. 1970 Jan;19(1):45-9. doi: 10.2337/diab.19.1.45.

Inhibition of intestinal sugar transport by phenformin.苯乙双胍对肠道糖转运的抑制作用。

Rev Esp Fisiol. 1975 Dec;31(4):251-4.

[Biochemical, histochemical, histological and functional studies on the effect of phenformin on small intestine mucosa in rat and man].[苯乙双胍对大鼠和人体小肠黏膜作用的生化、组织化学、组织学及功能研究]

Verh Dtsch Ges Inn Med. 1971;77:532-3.

[Impairment of intestinal glucose absorption by biguanide derivatives].[双胍类衍生物对肠道葡萄糖吸收的损害]

Acta Diabetol Lat. 1969 Sep;6 Suppl 1:636-43.

Inhibition of glucose absorption by 3-phenylpropylaminoguanidine-HCl (SaH 43-522) in laboratory animals.盐酸3-苯丙基氨基胍（SaH 43-522）对实验动物葡萄糖吸收的抑制作用。

Arch Int Pharmacodyn Ther. 1977 Oct;229(2):337-50.

Effect of phenformin on carbohydrate absorption in man.苯乙双胍对人体碳水化合物吸收的影响。

Diabetes. 1974 Aug;23(8):716-8. doi: 10.2337/diab.23.8.716.

Comparison of McN-3495 [N-(1-methyl-2-pyrrolidinylidene)-N'-phenyl-1-pyrrolidinecarboximidamide], a new, orally effective, hypoglycemic agent, with the biguanides.新型口服有效降糖药 McN-3495 [N-(1-甲基-2-吡咯烷叉基)-N'-苯基-1-吡咯烷甲脒] 与双胍类药物的比较。

Diabetes. 1978 Aug;27(8):868-76. doi: 10.2337/diab.27.8.868.

Mechanism of action of phenetylbiguanide (phenformin) in normal subjects. II. Intestinal absorption versus nonintestinal effects.苯乙双胍（降糖灵）在正常受试者中的作用机制。II. 肠道吸收与非肠道效应

Metabolism. 1974 Apr;23(4):349-58. doi: 10.1016/0026-0495(74)90053-5.

Phenformin-induced alterations of small intestinal function and mitochondrial structure in man.苯乙双胍对人体小肠功能和线粒体结构的影响。

J Lab Clin Med. 1973 Aug;82(2):195-200.

引用本文的文献

A Structural Basis for Biguanide Activity.双胍活性的结构基础。

Biochemistry. 2017 Sep 12;56(36):4786-4798. doi: 10.1021/acs.biochem.7b00619. Epub 2017 Aug 29.

Inhibition of intestinal absorption and improvement of oral glucose tolerance by biguanides in the normal and in the streptozotocin-diabetic rat.双胍类药物对正常大鼠及链脲佐菌素诱导的糖尿病大鼠肠道吸收的抑制作用及口服葡萄糖耐量的改善作用

Diabetologia. 1971 Jun;7(3):195-203. doi: 10.1007/BF01212553.

Analysis of the inhibitory effect of biguanides on glucose absorption: inhibition of active sugar transport.双胍类药物对葡萄糖吸收的抑制作用分析：对活性糖转运的抑制

Diabetologia. 1971 Oct;7(5):379-85. doi: 10.1007/BF01219474.

Inhibition of gluconeogenesis from lactate by phenylethylbiguanide in the perfused guinea pig liver.苯乙双胍对豚鼠离体灌流肝脏中由乳酸生成葡萄糖的抑制作用。

Diabetologia. 1972 Apr;8(2):117-24. doi: 10.1007/BF01235636.

The effect of dimethylbiguanide on glucose tolerance, serum insulin and growth hormone in obese patients.二甲双胍对肥胖患者糖耐量、血清胰岛素及生长激素的影响。

Diabetologia. 1972 Feb;8(1):1-7. doi: 10.1007/BF01219979.

Malabsorption of vitamin B12 in diabetic patients treated with phenformin: a comparison with metformin.接受苯乙双胍治疗的糖尿病患者维生素B12吸收不良：与二甲双胍的比较。

Br Med J. 1973 Sep 29;3(5882):673-5. doi: 10.1136/bmj.3.5882.673.

Inhibition of intestinal amino acid transport by blood sugar lowering biguanides.降糖双胍类药物对肠道氨基酸转运的抑制作用。

Diabetologia. 1973 Feb;9(1):6-12. doi: 10.1007/BF01225993.

[Biochemical, histochemical, histological and functional studies on the effect of phenformin on small intestine mucosa in rat and in man].[苯乙双胍对大鼠和人体小肠黏膜作用的生化、组织化学、组织学及功能研究]

Klin Wochenschr. 1973 Mar 1;51(5):235-41. doi: 10.1007/BF01467773.

The effect of biguanides on secretion and biosynthesis of insulin in isolated pancreatic islets of rats.双胍类药物对大鼠离体胰岛胰岛素分泌及生物合成的影响。

Diabetologia. 1972 Dec;8(6):402-7. doi: 10.1007/BF01212167.

Phenethylbiguanide and the inhibition of hepatic gluconeogenesis in the guinea pig.苯乙双胍与豚鼠肝糖异生的抑制作用

Biochem J. 1974 Oct;144(1):49-57. doi: 10.1042/bj1440049.

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