Collins P, Woollam D H
J Anat. 1979 Oct;129(Pt 3):623-31.
The subcommissural organ of the rat has been studied by a combination of light, scanning and transmission electron microscopy. Special attention has been paid to the appearance of the ventricular surface of the organ. The ependyma-derived cells on the surface of the organ are extremely long with a width which diminishes steadily from the base, where the nucleus is situated, to the ventricular surface. This results in a fan-shaped arrangement of cells, the cytoplasm of each cell reaching the surface of the ventricular system. The apical surface of the cell has small ciliated extensions 1-1.5 micrometers in diameter protruding into the ventricular lumen. With conspicuous rough endoplasmic reticulum and Golgi apparatus, and microtubules in profusion, the subcommissural organ cells possess the hallmarks of active secreting cells. The surface of the cells shows pinocytic vesicles-suggesting exchange of materials with the cerebrospinal fluid.
采用光学显微镜、扫描电子显微镜和透射电子显微镜相结合的方法对大鼠的联合下器官进行了研究。特别关注了该器官脑室表面的外观。器官表面由室管膜衍生的细胞非常长，其宽度从细胞核所在的基部到脑室表面逐渐减小。这导致细胞呈扇形排列，每个细胞的细胞质到达脑室系统的表面。细胞的顶端表面有直径为1 - 1.5微米的小纤毛状突起伸入脑室腔。联合下器官的细胞具有明显的粗面内质网、高尔基体和大量微管，具备活跃分泌细胞的特征。细胞表面可见吞饮小泡，提示与脑脊液进行物质交换。
