半合成β-内酰胺抗生素。II. 萘系列中的头孢菌素衍生物。化学和微生物学性质。
Semisynthetic beta-lactam antibiotics. II Cephalosporin derivatives in the naphthalene series. Chemical and microbiological properties.
作者信息
Quaresima E, Tinti M O, Foresta P, De Witt P, Ramacci M T
出版信息
J Antibiot (Tokyo). 1979 Dec;32(12):1311-8. doi: 10.7164/antibiotics.32.1311.
PMID:541255
Abstract
A seris of new 7-acylamidocephalosporins, containing a substituted naphthalene moiety in the side chain, has been prepared and tested for their in vitro antibacterial activity. Some observations are made on the structure-activity relationships.
摘要
一系列新的7-酰胺基头孢菌素已被制备出来，其侧链含有一个取代萘部分，并对它们的体外抗菌活性进行了测试。对构效关系进行了一些观察。
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