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[卡介苗补体结合试验在利什曼病诊断中的应用]

[The complement fixation test with BCG in the diagnosis of leishmaniasis].

作者信息

Mansueto S, Migneco G, La Cascia C

出版信息

Boll Ist Sieroter Milan. 1975 Jun 26;54(2):140-4.

PMID:54183
Abstract

The utility of complement-fixation test with an antigen from commercially lyophilized BCG was investigated in the diagnosis of leishmaniasis. The following results were obtained: Visceral leishmaniasis: 4 positivity on 5 cases; Oriental sore: 3 positivity on 6 cases; Canine leishmaniasis: 6 positivity, at high level, and 2 negativity; Other diseases: 5 positivity, on 17 sera of tbc; No positivity in sera from patients with various diseases, in control and in normal dogs. The results are compared with those quoted in medical literature and discussed. The meaning of the reaction is also briefly discussed, and the hypothesis of the presence of partigens between BCG and leishmania, or presence of autoantibodies is prospected.

摘要

研究了使用来自商业冻干卡介苗的抗原进行补体结合试验在利什曼病诊断中的效用。获得了以下结果:内脏利什曼病:5例中有4例呈阳性;东方疖:6例中有3例呈阳性;犬利什曼病:6例呈高水平阳性,2例阴性;其他疾病:在17份肺结核血清中有5例呈阳性;在患有各种疾病的患者血清、对照血清和正常犬血清中均未呈阳性。将结果与医学文献中引用的结果进行了比较并进行了讨论。还简要讨论了该反应的意义,并探讨了卡介苗与利什曼原虫之间存在部分抗原或存在自身抗体的假设。

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