Wharton C F, Bescos L L
Br Heart J. 1970 May;32(3):344-9. doi: 10.1136/hrt.32.3.344.
The movement of the anterior leaflet of the mitral valve has been recorded with an ultrasound echo technique. The intrinsic mobility of the valve cusps and the rate of ventricular filling are thought to influence the closure of the valve during diastole. Atrial contraction occurs at the end of ventricular diastole and reopens the valve before the mitral valve returns to the closed position before the onset of ventricular systole. The relation of the opening snap and third heart sound to the movement of the cusp is shown. In mitral stenosis ventricular systole occurs when the mitral valve is still far away from the closed position and the rapid movement of the cusp to the closed position may be the cause of the high intensity vibrations of the first heart sound. The EF slope (representing the rate of the closing movement of the cusp in end diastole) is decreased and a good correlation has been found with the degree of stenosis. After mitral valvotomy the EF slope increases significantly. The validity of these methods in assessing mitral incompetence or relative predominance of stenosis or incompetence in mixed mitral lesions is discussed. The ultrasound cardiograph is a fairly simple and completely atraumatic technique with proven diagnostic value in mitral valve disease. In addition, because of the new type of information that is given, it has potential as a research tool which is, as yet, largely unexplored.
已用超声回波技术记录了二尖瓣前叶的运动。瓣膜尖的固有活动度和心室充盈速率被认为会影响舒张期瓣膜的关闭。心房收缩发生在心室舒张末期，在心室收缩开始前二尖瓣回到关闭位置之前重新打开瓣膜。显示了开瓣音和第三心音与瓣膜尖运动的关系。在二尖瓣狭窄时，心室收缩发生在二尖瓣仍远离关闭位置时，瓣膜尖快速移向关闭位置可能是第一心音高强度振动的原因。EF斜率（代表舒张末期瓣膜尖关闭运动的速率）降低，且与狭窄程度有良好的相关性。二尖瓣切开术后，EF斜率显著增加。讨论了这些方法在评估二尖瓣关闭不全或混合性二尖瓣病变中狭窄或关闭不全的相对优势方面的有效性。超声心动图是一种相当简单且完全无创的技术，在二尖瓣疾病中具有已被证实的诊断价值。此外，由于所提供的新型信息，它有潜力成为一种研究工具，而目前在很大程度上尚未被探索。
