利血平治疗及去神经支配对豚鼠输精管离子分布的影响。
The effect of reserpine treatment and decentralization on the ion distribution in the vas deferens of the guinea-pig.
作者信息
Westfall D P
出版信息
Br J Pharmacol. 1970 May;39(1):121-7. doi: 10.1111/j.1476-5381.1970.tb09561.x.
Abstract
- The ion distribution in the vas deferens of the guinea-pig was determined following reserpine treatment and decentralization, procedures known to increase the sensitivity of this muscle to drug stimulation.2. There were no significant changes in the estimated intracellular ion concentrations following the two procedures. The half-times of (42)K and (36)Cl effluxes were also unaltered.3. As far as ion content is concerned there is no basis for suggesting an altered resting membrane potential in supersensitive smooth muscle.
摘要
在豚鼠输精管中，采用利血平处理和去神经支配后测定离子分布，已知这些操作会增加该肌肉对药物刺激的敏感性。
经过这两种操作后，估计的细胞内离子浓度没有显著变化。(42)K和(36)Cl外流的半衰期也未改变。
就离子含量而言，没有依据表明超敏平滑肌的静息膜电位发生了改变。
相似文献
1
The effect of reserpine treatment and decentralization on the ion distribution in the vas deferens of the guinea-pig.利血平治疗及去神经支配对豚鼠输精管离子分布的影响。
Br J Pharmacol. 1970 May;39(1):121-7. doi: 10.1111/j.1476-5381.1970.tb09561.x.
2
Effects of sympathetic denervation or chronic reserpine on potassium (42K) and chloride (36Cl) efflux from guinea-pig vas deferens.交感神经去神经支配或长期使用利血平对豚鼠输精管钾（42K）和氯（36Cl）外流的影响。
Eur J Pharmacol. 1980 Aug 22;66(1):11-9. doi: 10.1016/0014-2999(80)90290-3.
3
Nonspecific supersensitivity of the guinea-pig vas deferens produced by decentralization and reserpine treatment.去神经支配和利血平处理引起的豚鼠输精管非特异性超敏反应
Br J Pharmacol. 1970 May;39(1):110-20. doi: 10.1111/j.1476-5381.1970.tb09560.x.
4
Ion content and ion fluxes in the smooth muscle cells of the longitudinal layer of the guinea-pig's vas deferens.豚鼠输精管纵行肌层平滑肌细胞中的离子含量与离子通量
Pflugers Arch. 1969;313(2):95-105. doi: 10.1007/BF00586238.
5
6
7
Involvement of the sodium-potassium pump in the mechanism of postjunctional supersensitivity of the vas deferens of the guinea pig.钠钾泵参与豚鼠输精管节后超敏反应的机制。
J Pharmacol Exp Ther. 1979 Jul;210(1):27-36.
8
The effect of loop diuretics on Cl- transport in smooth muscle of the guinea-pig vas deferens and taenia from the caecum.袢利尿剂对豚鼠输精管和平滑肌及盲肠带中氯离子转运的影响。
J Physiol. 1990 Feb;421:33-53. doi: 10.1113/jphysiol.1990.sp017932.
9
Effect of postganglionic denervation and pretreatment with reserpine on alpha-adrenoceptors of the guinea-pig vas deferens.节后去神经支配及利血平预处理对豚鼠输精管α-肾上腺素能受体的影响。
Pharmacology. 1985;30(5):289-95. doi: 10.1159/000138080.
10
Morphological and biochemical changes in supersensitive smooth muscle.超敏平滑肌的形态学和生化变化
Fed Proc. 1975 Sep;34(10):1985-9.
本文引用的文献
1
MEMBRANE POTENTIAL AND IONIC CONTENT IN PREGNANT AND NON-PREGNANT RAT MYOMETRIUM.妊娠和未妊娠大鼠子宫肌层的膜电位与离子含量
J Physiol. 1965 Mar;177(2):263-87. doi: 10.1113/jphysiol.1965.sp007591.
2
THE EFFECT OF ADRENALINE ON THE SMOOTH MUSCLE OF GUINEA-PIG TAENIA COLI IN RELATION TO THE DEGREE OF STRETCH.肾上腺素对豚鼠结肠带平滑肌的作用与拉伸程度的关系
J Physiol. 1963 Nov;169(1):198-212. doi: 10.1113/jphysiol.1963.sp007250.
3
A possible role for tissue calcium in reserpine supersensitivity.组织钙在利血平超敏反应中的可能作用。
J Pharmacol Exp Ther. 1967 Jan;155(1):42-9.
4
The effect of temperature on the membrane conductance of the smooth muscle of the guinea-pig taenia coli.温度对豚鼠结肠带平滑肌膜电导的影响。
J Physiol. 1969 Feb;200(3):621-35. doi: 10.1113/jphysiol.1969.sp008712.
5
Membrane potential and ion content in cat and guinea-pig myometrium and the response to adrenaline and noradrenaline.猫和豚鼠子宫肌层的膜电位、离子含量以及对肾上腺素和去甲肾上腺素的反应。
Br J Pharmacol. 1968 Oct;34(2):388-407. doi: 10.1111/j.1476-5381.1968.tb07060.x.
6
Nonspecific supersensitivity of the guinea-pig vas deferens produced by decentralization and reserpine treatment.去神经支配和利血平处理引起的豚鼠输精管非特异性超敏反应
Br J Pharmacol. 1970 May;39(1):110-20. doi: 10.1111/j.1476-5381.1970.tb09560.x.
7
Distribution and kinetics of CoEDTA in smooth muscle, and its use as an extracellular marker.钴乙二胺四乙酸（CoEDTA）在平滑肌中的分布与动力学及其作为细胞外标志物的应用。
J Physiol. 1969 Feb;200(2):387-401. doi: 10.1113/jphysiol.1969.sp008700.
8
A relatively nonspecific supersensitivity in aortic strips resulting from pretreatment with reserpine.用利血平预处理后，主动脉条出现相对非特异性的超敏反应。
J Pharmacol Exp Ther. 1966 Jul;153(1):70-80.
Zotero 插件