Sutter R P
Science. 1970 Jun 26;168(3939):1590-2. doi: 10.1126/science.168.3939.1590.
Cultures of the (-) strain of Blakeslea trispora synthesize trisporic acid C, a sex hormone, from precursors made by cultures of the (+) strain. The precursors are nonacidic compounds isolated from the culture medium of the (+) strain by chloroform extraction. Actidione does not inhibit trisporic acid synthesis from isolated precursors, suggesting that the enzymes involved in the synthesis in cultures of the (-) strain are constitutive.
三孢布拉氏霉菌(-)菌株的培养物从(+)菌株培养物产生的前体合成性激素三孢酸C。这些前体是通过氯仿萃取从(+)菌株的培养基中分离出的非酸性化合物。放线菌酮不抑制从分离出的前体合成三孢酸,这表明(-)菌株培养物中参与合成的酶是组成型的。