Bachmann H, Lössner J, Gruss B, Ruchholtz U
Psychiatr Neurol Med Psychol (Leipz). 1979 Jul;31(7):393-400.
Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling.
1949年至1977年11月30日期间，德意志民主共和国共登记了123例威尔逊氏病患者。根据现有统计数据，假设哈迪-温伯格定律在很大程度上适用，该病的发病率约为2.9/10万，基因频率约为0.53%，杂合子发病率为1.05%。从现有资料中得出结论，以期今后能够发现该病并进行遗传家庭咨询。
