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[三碘甲状腺原氨酸、甲状腺素和甲基硫氧嘧啶短期治疗对大鼠血浆和肝脏脂质水平的影响(作者译)]

[Effects of T3, T4 and methyltiouracile short-term treatments on plasma and liver lipid levels in rats (author's transl)].

作者信息

Macarulla J M, Abad C, Lacort M, Ochoa B

出版信息

Rev Esp Fisiol. 1979 Dec;35(4):421-6.

PMID:542704
Abstract

The effects of short-term administration of thyroid hormones (T3 and T4) and methyltiouracile (MTU) on liver and plasma lipid levels in female rats have been comparatively studied T3 increases the levels of all the studied liver lipids and decreases the plasma lipids. T4 produces smaller and even, in some cases (liver triglycerides and cholesterol esters), opposite effects. The administration of MTU produces, in general, opposite effects to T3 and T4.

摘要

对雌性大鼠短期给予甲状腺激素(T3和T4)及甲基硫氧嘧啶(MTU)对肝脏和血浆脂质水平的影响进行了比较研究。T3会使所有研究的肝脏脂质水平升高,并降低血浆脂质水平。T4产生的影响较小,在某些情况下(肝脏甘油三酯和胆固醇酯)甚至产生相反的影响。一般来说,MTU的给药产生与T3和T4相反的效果。

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