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孕酮对大鼠血浆及肝脏脂质水平的影响(作者译)

[Effect of progesterone on rat plasma and liver lipid levels (author's transl)].

作者信息

Gandarias J M, Abad C, Lacort M, Ochoa B

出版信息

Rev Esp Fisiol. 1979 Dec;35(4):470-3.

PMID:542709
Abstract

The effect of progesterone upon several lipidic parameters on rat liver and plasma was studied. Progesterone administration led to a significant increase in the hepatic triacylglyceride and cholesterol esterified levels and to a decrease in the phospholipid content. After progesterone treatment decreases in plasma total lipids, phospholipids, cholesterol and cholesterol esterified were observed, whereas plasma triacylglyceride and free fatty acid levels increased. The hormonal treatment altered the lipoprotein pattern, which significantly reduced the beta-lipoprotein fraction.

摘要

研究了孕酮对大鼠肝脏和血浆中几种脂质参数的影响。给予孕酮导致肝脏三酰甘油和胆固醇酯化水平显著升高,磷脂含量降低。孕酮治疗后,血浆总脂质、磷脂、胆固醇和胆固醇酯化水平降低,而血浆三酰甘油和游离脂肪酸水平升高。激素治疗改变了脂蛋白模式,显著降低了β-脂蛋白部分。

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