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疱疹样皮炎患者亲属的小肠黏膜异常

Small intestinal mucosal abnormalities in relatives of patients with dermatitis herpetiformis.

作者信息

Marks J, Birkett D, Shuster S, Roberts D F

出版信息

Gut. 1970 Jun;11(6):493-7. doi: 10.1136/gut.11.6.493.

DOI:10.1136/gut.11.6.493
PMID:5430375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1553043/
Abstract

Jejunal biopsy has been carried out in 19 relatives of patients with dermatitis herpetiformis and stereomicroscopic abnormalities have been found in seven. The majority of the relatives in whom these abnormalities were found had no bowel symptoms: one had the rash of dermatitis herpetiformis. All but one of the propositi of the relatives in whom were found small intestinal mucosal abnormalities themselves had the coeliac syndrome. It is concluded that a genetic factor is involved in the production of the enteropathy of dermatitis herpetiformis as in other forms of the coeliac syndrome.

摘要

对19名疱疹样皮炎患者的亲属进行了空肠活检,其中7人发现有立体显微镜下的异常。发现这些异常的大多数亲属没有肠道症状:1人有疱疹样皮炎皮疹。在发现有小肠黏膜异常的亲属中,除1人外,所有先证者本身都患有乳糜泻综合征。结论是,与其他形式的乳糜泻综合征一样,遗传因素参与了疱疹样皮炎肠病的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/223f/1553043/e0e84a5448ed/gut00684-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/223f/1553043/e0e84a5448ed/gut00684-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/223f/1553043/e0e84a5448ed/gut00684-0049-a.jpg

相似文献

1
Small intestinal mucosal abnormalities in relatives of patients with dermatitis herpetiformis.疱疹样皮炎患者亲属的小肠黏膜异常
Gut. 1970 Jun;11(6):493-7. doi: 10.1136/gut.11.6.493.
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Patchiness and duodenal-jejunal variation of the mucosal abnormality in coeliac disease and dermatitis herpetiformis.乳糜泻和疱疹样皮炎中黏膜异常的斑片状及十二指肠-空肠变异
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引用本文的文献

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Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation.乳糜泻与神经表现:从麸质到神经炎症。
Int J Mol Sci. 2022 Dec 8;23(24):15564. doi: 10.3390/ijms232415564.
2
Dermatitis herpetiformis.疱疹样皮炎
Springer Semin Immunopathol. 1981 Jun;4(1):33-43. doi: 10.1007/BF01891883.
3
Incidence of small-intestinal mucosal abnormalities and of clinical coeliac disease in the relatives of children with coeliac disease.乳糜泻患儿亲属中小肠黏膜异常及临床乳糜泻的发病率。

本文引用的文献

1
SMALL-INTESTINAL AND GASTRIC ABNORMALITIES IN ULCERATIVE COLITIS.溃疡性结肠炎的小肠和胃部异常
Br Med J. 1965 Mar 27;1(5438):827-31. doi: 10.1136/bmj.1.5438.827.
2
COMPARISON OF JEJUNAL MUCOSA IN POST-GASTRECTOMY STATES, IDIOPATHIC STEATORRHOEA, AND CONTROLS USING THE DISSECTING MICROSCOPE AND CONVENTIONAL HISTOLOGICAL METHODS.使用解剖显微镜和传统组织学方法对胃切除术后状态、特发性脂肪泻及对照组的空肠黏膜进行比较
Gut. 1964 Dec;5(6):553-62. doi: 10.1136/gut.5.6.553.
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STUDIES OF THE FAMILIAL NATURE OF CELIAC SPRUE USING BIOPSY OF THE SMALL INTESTINE.
Gut. 1971 Oct;12(10):789-93. doi: 10.1136/gut.12.10.789.
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Intestinal malabsorption and the skin.肠道吸收不良与皮肤
Gut. 1971 Nov;12(11):938-47. doi: 10.1136/gut.12.11.938.
使用小肠活检对乳糜泻家族性本质的研究。
N Engl J Med. 1965 Mar 4;272:448-56. doi: 10.1056/NEJM196503042720903.
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OBSERVATIONS ON JEJUNAL BIOPSY IN UGANDAN AFRICANS.
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The inheritance of coeliac disease.乳糜泻的遗传
Ann Hum Genet. 1959 Jul;23:266-78. doi: 10.1111/j.1469-1809.1959.tb01470.x.
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Intraluminal biopsy of the small intestine; the intestinal biopsy capsule.小肠腔内活检;肠道活检胶囊
Am J Dig Dis. 1957 May;2(5):236-41. doi: 10.1007/BF02231100.
7
Structure and function of the small intestine in dermatitis herpetiformis.疱疹样皮炎中小肠的结构与功能
Br J Dermatol. 1967 Oct;79(10):509-18. doi: 10.1111/j.1365-2133.1967.tb11405.x.
8
A study of proximal and distal intestinal structure and absorptive function in idiopathic steatorrhoea.特发性脂肪泻患者近端及远端肠道结构与吸收功能的研究
Q J Med. 1967 Jul;36(143):425-44.
9
Jejunal biopsy in patients with malabsorptive disease.吸收不良疾病患者的空肠活检。
Scott Med J. 1966 Oct;11(10):343-55. doi: 10.1177/003693306601101001.
10
Appearances of the jejunal mucosa in acute tropical sprue in Singapore.新加坡急性热带口炎性腹泻患者空肠黏膜的表现。
Gut. 1966 Apr;7(2):128-39. doi: 10.1136/gut.7.2.128.