• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Protocollagen proline hydroxylase of the mouse uterus during pregnancy and post-partum involution.妊娠及产后子宫复旧期间小鼠原胶原蛋白脯氨酸羟化酶
Biochem J. 1970 Feb;116(3):367-9. doi: 10.1042/bj1160367.
2
[Studies on prolyl hydroxylase activity, hydroxyproline content and solubility of collagen in the human uterus during pregnancy, delivery and postpartum involution (author's transl)].[关于妊娠、分娩及产后子宫复旧过程中人体子宫内脯氨酰羟化酶活性、羟脯氨酸含量及胶原蛋白溶解性的研究（作者译）]
Nihon Sanka Fujinka Gakkai Zasshi. 1981 Oct;33(10):1703-10.
3
Collagen biosynthesis. Characterization of subcellular fractions from embyonic chick fibroblasts and the intracellular localization of protocollagen prolyl and protocollagen lysyl hydroxylases.胶原蛋白生物合成。胚胎鸡成纤维细胞亚细胞组分的特性以及原胶原蛋白脯氨酰羟化酶和原胶原蛋白赖氨酰羟化酶的细胞内定位。
Biochem J. 1974 Oct;144(1):123-30. doi: 10.1042/bj1440123.
4
Connective tissue. XVII. Protocollagen hydroxylase of pig uterus.结缔组织。十七。猪子宫原胶原羟化酶。
Biochim Biophys Acta. 1968 Mar 25;151(3):568-72. doi: 10.1016/0005-2744(68)90003-x.
5
[Hepatic protocollagen proline hydroxylase].[肝原胶原脯氨酸羟化酶]
Saishin Igaku. 1969 Jan 10;24(1):164-8.
6
Acid hydrolases of the rat uterus in relation to pregnancy, post-partum involution and collagen breakdown.大鼠子宫酸性水解酶与妊娠、产后 involution 和胶原蛋白分解的关系。 注：“involution”在医学领域可能有特定含义，比如“复旧”等，需结合具体语境准确理解。这里直接保留英文以便能完整准确传达原文信息。
Biochem J. 1965 Dec;97(3):855-66. doi: 10.1042/bj0970855.
7
Effect of endometrial phase, ovariectomy, estradiol and progesterone on uterine protocollagen hydroxylase.子宫内膜期、卵巢切除术、雌二醇和孕酮对子宫原胶原羟化酶的影响。
Endocrinology. 1969 Dec;85(6):1057-61. doi: 10.1210/endo-85-6-1057.
8
Protocollagen proline hydroxylase activity in the skin of normal human subjects and of patients with scleroderma.正常人及硬皮病患者皮肤中原胶原脯氨酸羟化酶的活性
Scand J Clin Lab Invest. 1969 May;23(3):241-7. doi: 10.3109/00365516909077656.
9
Collagen proline hydroxylase activity in the uterus of the rat during rapid collagen synthesis in vivo.大鼠子宫在体内快速胶原合成过程中的胶原脯氨酸羟化酶活性。
Arch Biochem Biophys. 1973 Feb;154(2):583-92. doi: 10.1016/0003-9861(73)90012-x.
10
Increased protocollagen proline hydroxylase activity in synovial tissue in rheumatoid arthritis.类风湿关节炎患者滑膜组织中原胶原蛋白脯氨酸羟化酶活性增加。
Clin Chim Acta. 1970 Dec;30(3):741-4. doi: 10.1016/0009-8981(70)90269-x.

引用本文的文献

1
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.脯氨酰4-羟化酶活性响应转录因子：从羟基化到基因表达及神经保护
Front Biosci. 2008 Jan 1;13:2875-87. doi: 10.2741/2892.
2
Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies.人肝活检组织中胶原蛋白脯氨酸羟化酶活性及35S硫酸盐摄取情况
Gut. 1974 Apr;15(4):260-7. doi: 10.1136/gut.15.4.260.
3
Liver protocollagen proline hydroxylase in human liver diseases and experimental liver fibrosis.人类肝脏疾病及实验性肝纤维化中的肝脏原胶原脯氨酸羟化酶
Gastroenterol Jpn. 1977;12(1):21-7. doi: 10.1007/BF02773998.

本文引用的文献

1
Enzymatic hydroxylation of proline and lysine in protocollagen.原胶原蛋白中脯氨酸和赖氨酸的酶促羟基化作用。
Proc Natl Acad Sci U S A. 1967 Mar;57(3):782-9. doi: 10.1073/pnas.57.3.782.
2
Alteration in the collagen content of the human uterus during pregnancy and post partum involution.孕期及产后子宫复旧过程中人体子宫胶原蛋白含量的变化。
J Exp Med. 1962 Feb 1;115(2):357-65. doi: 10.1084/jem.115.2.357.
3
Studies on uterine collagen during pregnancy and puerperium.孕期及产褥期子宫胶原蛋白的研究。
Lab Invest. 1961 Nov-Dec;10:1240-58.
4
A SIMPLE METHOD FOR DIFFERENTIAL ASSAY OF TRITIUM AND CARBON-14 IN WATER-SOLUBLE BIOLOGICAL MATERIALS.一种用于水溶性生物材料中氚和碳-14 差异分析的简单方法。
Anal Biochem. 1963 Sep;6:263-71. doi: 10.1016/0003-2697(63)90134-9.
5
Connective tissue. IV. Synthesis and turnover of proteins in tissues of rats.结缔组织。IV. 大鼠组织中蛋白质的合成与周转
Proc Soc Exp Biol Med. 1961 Jan;106:121-4. doi: 10.3181/00379727-106-26257.
6
Connective tissue V. Comparison of synthesis and turnover of collagen and elastin in tissues of rat at several ages.结缔组织V. 不同年龄大鼠组织中胶原蛋白和弹性蛋白合成与更新的比较。
Proc Soc Exp Biol Med. 1961 Feb;106:335-8. doi: 10.3181/00379727-106-26329.
7
The colorimetric estimation of alpha-amino nitrogen in tissue fluids.组织液中α-氨基氮的比色测定
J Clin Pathol. 1959 Jan;12(1):80-4. doi: 10.1136/jcp.12.1.80.
8
Studies on the stability of protocollagen hydroxylase.原胶原羟化酶稳定性的研究。
FEBS Lett. 1968 Sep;1(4):223-226. doi: 10.1016/0014-5793(68)80067-5.
9
Investigations on collagen proline hydroxylation in a cell-free system.无细胞体系中胶原蛋白脯氨酸羟化作用的研究。
Biochim Biophys Acta. 1967 Dec 12;147(3):487-96. doi: 10.1016/0005-2795(67)90008-6.
10
Hydroxylation of proline in synthetic polypeptides with purified protocollagen hydroxylase.用纯化的原胶原羟化酶对合成多肽中的脯氨酸进行羟化反应。
J Biol Chem. 1967 Sep 25;242(18):4007-12.

妊娠及产后子宫复旧期间小鼠原胶原蛋白脯氨酸羟化酶

Protocollagen proline hydroxylase of the mouse uterus during pregnancy and post-partum involution.

作者信息

Halme J, Jääskeläinen M

出版信息

Biochem J. 1970 Feb;116(3):367-9. doi: 10.1042/bj1160367.

DOI:10.1042/bj1160367
PMID:5435684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1185374/
Abstract
  1. The protocollagen proline hydroxylase in mouse uterus was found to be similar to that in other animal sources in its subcellular distribution and cofactor requirements. 2. The activities of this enzyme in uterine tissue from non-pregnant mice were comparable with those in various embryonic tissues. 3. In the second half of pregnancy the protocollagen proline hydroxylase activity increased markedly. 4. After parturition the activity of this enzyme decreased rapidly, reaching normal non-pregnant values at 24h post partum. The results suggest a good correlation between the synthesis of collagen and the activity of protocollagen proline hydroxylase.
摘要
  1. 发现小鼠子宫中的原胶原脯氨酸羟化酶在亚细胞分布和辅助因子需求方面与其他动物来源的该酶相似。2. 未孕小鼠子宫组织中这种酶的活性与各种胚胎组织中的活性相当。3. 在妊娠后半期，原胶原脯氨酸羟化酶活性显著增加。4. 分娩后，这种酶的活性迅速下降，在产后24小时达到未孕时的正常水平。结果表明胶原蛋白的合成与原胶原脯氨酸羟化酶的活性之间有良好的相关性。