Haber B, Kuriyama K, Roberts E
Science. 1970 May 1;168(3931):598-9. doi: 10.1126/science.168.3931.598.
Human glial cells grown in culture and gliomas and white matter contain an l-glutamic acid decarboxylase which is stimulated markedly by carbonyl-trapping agents. In contrast, L-glutamic acid decarboxylase activity of human cerebral gray matter is strongly inhibited by carbonyl-trapping agents. These results suggest a glial localization of the new type of l-glutamic acid decarboxylase.
在培养物中生长的人类神经胶质细胞、神经胶质瘤和白质含有一种L-谷氨酸脱羧酶，该酶受到羰基捕获剂的显著刺激。相比之下，人类大脑灰质的L-谷氨酸脱羧酶活性受到羰基捕获剂的强烈抑制。这些结果表明新型L-谷氨酸脱羧酶定位于神经胶质细胞。
