Widow W, Lehr V
Arch Geschwulstforsch. 1979;49(6):535-43.
Correlations between obesity and prognosis of operated cancer of the breast have not been investigated until now. In 491 patients operated upon by radical mastectomy (1968 to 1972) it can be demonstrated that in patients in whom the weight of the resected breast is above 1100 g the survival rates are more unfavourable than in other cases. As to tumor size and invasion of lymphnodes the distribution in the group with "heavy breasts" is more unfavourable than in the other groups. The causes of the differences in survival may be attributed to worsened conditions for detection of cancer in cases with large breasts as well as to alterations of hormone production and metabolism in connection with nutritional factors.
迄今为止，尚未对肥胖与乳腺癌手术预后之间的相关性进行研究。在491例行根治性乳房切除术的患者中（1968年至1972年），可以证明，切除乳房重量超过1100克的患者，其生存率比其他情况更差。至于肿瘤大小和淋巴结侵犯情况，“乳房较大”组的分布比其他组更不利。生存差异的原因可能归因于乳房较大病例中癌症检测条件变差，以及与营养因素相关的激素产生和代谢改变。
