同胞中的短暂性新生儿糖尿病
Transient neonatal diabetes mellitus in sibs.
作者信息
Ferguson A W, Milner R D
出版信息
Arch Dis Child. 1970 Feb;45(239):80-3. doi: 10.1136/adc.45.239.80.
Abstract
The occurrence of transient neonatal diabetes mellitus in successive male sibs is described. Both infants were small in relation to their periods of gestation and the placentas were abnormal. Subsequent investigation of the mother revealed a flat glucose tolerance curve with normal plasma insulin levels. Transient neonatal diabetes mellitus may be due to delayed matuiration of fetal δ-cells caused by a combination of maternal and placental factors.
摘要
本文描述了连续两个男性同胞发生短暂性新生儿糖尿病的情况。两名婴儿相对于其孕周均较小，且胎盘异常。对母亲的后续调查显示其葡萄糖耐量曲线平坦，血浆胰岛素水平正常。短暂性新生儿糖尿病可能是由母体和胎盘因素共同作用导致胎儿δ细胞成熟延迟所致。
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