口服利多卡因：其吸收情况及控制室性心律失常的有效性。
Oral lignocaine: its absorption and effectiveness in ventricular arrhythmia control.
作者信息
Parkinson P I, Margolin L, Dickson D S
出版信息
Br Med J. 1970 Apr 4;2(5700):29-30. doi: 10.1136/bmj.2.5700.29.
Abstract
A preliminary study suggests that the gastrointestinal absorption of lignocaine is predictable and that adequate antiarrhythmic blood concentrations are maintained for four to five hours when 500 mg. is taken with food and for two hours if the drug is taken without food. Ventricular arrhythmias were successfully treated with oral lignocaine in four patients.
摘要
一项初步研究表明，利多卡因的胃肠道吸收情况是可预测的，若与食物一起服用500毫克，可维持四至五小时的足够抗心律失常血药浓度；若空腹服用，则可维持两小时。四名患者口服利多卡因后，室性心律失常得到成功治疗。
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