维持性血液透析患者的头孢菌素血清水平。
Cephaloridine serum levels in patients on maintenance haemodialysis.
作者信息
Curtis J R, Marshall M J
出版信息
Br Med J. 1970 Apr 18;2(5702):149-51. doi: 10.1136/bmj.2.5702.149.
Abstract
Cephaloridine serum half-life was determined in 11 patients undergoing maintenance haemodialysis. Three of them were anephric. The mean cephaloridine half-life was 10.4 hours. There was an inverse correlation between cephaloridine half-life and the duration of maintenance haemodialysis treatment. Reasons for this are discussed.The effect of haemodialysis with the Kiil dialyser on cephaloridine half-life was studied in three patients.Dosage recommendations for patients on maintenance haemodialysis are suggested.
摘要
在11名接受维持性血液透析的患者中测定了头孢菌素血清半衰期。其中3人无肾。头孢菌素的平均半衰期为10.4小时。头孢菌素半衰期与维持性血液透析治疗时间呈负相关。讨论了其原因。在3名患者中研究了使用基尔透析器进行血液透析对头孢菌素半衰期的影响。建议了维持性血液透析患者的给药剂量。
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