Kato Y
Nihon Seikeigeka Gakkai Zasshi. 1979 Dec;53(12):1807-21.
In order to investigate the influences of artificial socket made of stainless-steel, pure titanium, high-density polyethylene (HDP), and polycrystal ceramics upon the articular cartilage of the femoral head, experimental artificial sockets were developed. This artificial socket was inserted into the hip joint in a dog, and the changes in the articular cartilage of the femoral head were studied at varying intervals after insertion of the socket. The results revealed that both the stainless-steel and the ceramic sockets caused slight atrophy and degeneration in the articular cartilage of the femoral head since one month after the operation, and these changes were increasingly more appreciable as time advanced. Any changes were hardly noted in the articular cartilage of the femoral head by titanium socket at the end of one month after the operation, whereas the HDP socket caused substantial changes. At the end of one year after the operation, marked degeneration was noted in the articular cartilage of the femoral head by socket made of stainless-steel, titanium, and HDP, and also the femoral head developed deformity. On the basis of the scanning electron microscopic findings on the surface of the articular cartilage of the femoral head affected by each of these artificial socket, and of the metal microscopic examinations of the surface of the artificial sockets, and furthermore on the basis of the findings of gradual deformation of femoral heads due to the artificial sockets, it was shown that articular cartilage of the femoral head was mainly influenced in the case of metallic socket and that both sides of the artificial socket and the articular cartilage of the femoral head were worn out in the case of HDP socket. The ceramic socket was found cracked, developing a loosening in some cases. In summary, it was concluded that the articular cartilage of the femoral head is affected by the artificial socket at a relatively early stage after its application despite materials of the sockets.
为了研究由不锈钢、纯钛、高密度聚乙烯（HDP）和多晶陶瓷制成的人工髋臼对股骨头关节软骨的影响，制作了实验性人工髋臼。将此人造髋臼植入犬的髋关节，并在植入髋臼后的不同时间间隔研究股骨头关节软骨的变化。结果显示，自手术后1个月起，不锈钢和陶瓷髋臼均导致股骨头关节软骨出现轻微萎缩和退变，且随着时间推移这些变化愈发明显。术后1个月结束时，钛制髋臼在股骨头关节软骨上几乎未引起任何变化，而HDP髋臼则导致了显著变化。术后1年结束时，由不锈钢、钛和HDP制成的髋臼在股骨头关节软骨上均出现明显退变，且股骨头出现畸形。基于受这些人工髋臼影响的股骨头关节软骨表面的扫描电子显微镜检查结果、人工髋臼表面的金相显微镜检查结果，此外基于因人工髋臼导致股骨头逐渐变形的检查结果，结果表明，在使用金属髋臼的情况下，股骨头关节软骨受到的影响较大，而在使用HDP髋臼的情况下，人工髋臼和股骨头关节软骨的两侧均出现磨损。发现陶瓷髋臼出现裂纹，在某些情况下出现松动。总之，得出的结论是，尽管髋臼材料不同，但在应用人工髋臼后相对早期阶段，股骨头关节软骨就会受到影响。
