流感病毒的M蛋白没有免疫作用。
The M protein of influenza viruses has no immunizing effect.
作者信息
Becht H, Gruschkau H, Rott R
出版信息
Med Microbiol Immunol. 1979;167(4):285-8. doi: 10.1007/BF02120814.
PMID:545115
Abstract
Influenza A virus M protein was prepared by electrophoresis in SDS polyacrylamide gel from virus particles which had been pretreated with octylglucoside to remove the surface glycoproteins; M antigens from the influenza virus strains A/Victoria/3/75 (H3N2), A/FPV/Rostock (Hav1N1) and A/chick/Germany/49 (Hav2Neq1) did not protect mice against a lethal challenge infection with the virulent Victoria strain.
摘要
甲型流感病毒M蛋白是通过十二烷基硫酸钠聚丙烯酰胺凝胶电泳从用辛基葡糖苷预处理以去除表面糖蛋白的病毒颗粒中制备的；来自甲型流感病毒株A/维多利亚/3/75（H3N2）、A/鸡瘟病毒/罗斯托克（Hav1N1）和A/鸡/德国/49（Hav2Neq1）的M抗原不能保护小鼠免受强毒株维多利亚株的致死性攻击感染。
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