孕激素在肾和子宫体转移性癌治疗中的应用。

Paine C H, Wright F W, Ellis F

Br J Cancer. 1970 Jun;24(2):277-82. doi: 10.1038/bjc.1970.31.

The effect of the progestogen medroxyprogesterone acetate on metastases from renal, endometrial and other tumours has been studied in 25 patients. Seven patients with renal and endometrial tumours had a useful response, pulmonary metastases and a large primary renal tumour showing the greatest effect. Bony metastases were unaffected by the drug and were treated by local radiotherapy. If a response occurred, it did so within 3 months.

已对25例患者研究了孕激素醋酸甲羟孕酮对肾、子宫内膜及其他肿瘤转移的影响。7例患有肾和子宫内膜肿瘤的患者有明显疗效，肺转移瘤以及原发性大肾肿瘤的疗效最为显著。骨转移不受该药物影响，采用局部放疗进行治疗。若有疗效，在3个月内即可显现。