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正常及白内障患者晶状体中游离型和蛋白结合型谷胱甘肽

Free and protein-bound glutathione in normal and cataractous human lenses.

作者信息

Harding J J

出版信息

Biochem J. 1970 May;117(5):957-60. doi: 10.1042/bj1170957.

Abstract

Protein-bound glutathione was identified and measured in normal and cataractous human lenses. In a major group of cataracto us lenses the bound glutathione concentration was higher than normal. Study of normal lenses showed that their glutathione content is age-dependent, decreasing steadily from about 3.5mumol/g of lens at age 20 years to about 1.8mumol/g of lens at age 65 years. Cataract brings further decreases.

摘要

在正常和患白内障的人眼中鉴定并测量了与蛋白质结合的谷胱甘肽。在一大组白内障眼中,结合型谷胱甘肽的浓度高于正常水平。对正常眼睛的研究表明,其谷胱甘肽含量与年龄有关,从20岁时约3.5微摩尔/克晶状体稳步下降至65岁时约1.8微摩尔/克晶状体。白内障会导致进一步下降。

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