Godfrey S, Edwards R H, Campbell E J, Newton-Howes J
Thorax. 1970 May;25(3):285-7. doi: 10.1136/thx.25.3.285.
A study of the relation between physical signs and the clinical and physiological pattern of chronic lung disease with obstruction has been carried out on 24 patients with varying degrees of airways obstruction. One sign (the forced expiratory time) was a direct reflection of the obstruction, but a number of other signs which also correlated significantly with the specific airway conductance were probably related to secondary effects on lung volume (increased resonance), disordered pattern of muscle action (tracheal tug and use of accessory muscles) or to excessive swings of intrathoracic pressure (excavation of supraclavicular fossae). Other signs which are regularly present but which did not correlate significantly with the severity of the airways obstruction were often related to other factors such as age or duration of symptoms (tracheal length). The difficulties in deciding the origin of other signs such as wheezes (rhonchi) or costal paradox are discussed.
对24例不同程度气道阻塞的慢性阻塞性肺病患者进行了一项关于体征与临床及生理模式之间关系的研究。一项体征（用力呼气时间）是阻塞的直接反映，但其他一些与比气道传导率也显著相关的体征，可能与对肺容量的继发影响（叩诊反响增强）、肌肉活动模式紊乱（气管牵拉和辅助肌使用）或胸内压过度波动（锁骨上窝凹陷）有关。其他经常出现但与气道阻塞严重程度无显著相关性的体征，往往与年龄或症状持续时间等其他因素有关（气管长度）。文中还讨论了确定诸如哮鸣音（干啰音）或肋间隙反常运动等其他体征来源的困难。
