长期饥饿——一种危险的做法？
Prolonged starvation--a dangerous procedure?
作者信息
Runcie J, Thomson T J
出版信息
Br Med J. 1970 Aug 22;3(5720):432-5. doi: 10.1136/bmj.3.5720.432.
Abstract
Experience with 18 obese patients who have undergone prolonged (60 days) therapeutic starvation shows that in general this is a safe procedure, but there are significant associated hazards, particularly a breakdown in electrolyte homoeostasis. The need for close biochemical control of such patients is stressed.
摘要
对18名接受长期（60天）治疗性饥饿的肥胖患者的经验表明，总体而言这是一个安全的程序，但存在重大的相关风险，尤其是电解质稳态的破坏。强调对此类患者进行密切生化监测的必要性。
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3
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4
Death during therapeutic starvation for obesity.
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5
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