Arnander C, Jurell G, Tornling G, Unge G
Scand J Plast Reconstr Surg. 1979;13(2):261-2. doi: 10.3109/02844317909013067.
The effect of dipyridamole (Persantin) on the survival of experimental skin flaps was studied. In controls 39% of the skin flap area survived. Intraperitoneal injection of dipyridamole 4 mg/kg twice daily starting four hours preoperatively increased the surviving area with 18%. This increase is statistically significant (p less than 0.05). The improved survival could be due to the vasodilatory action of the drug and/or proliferation of small bloodvessels induced by the drug.
研究了双嘧达莫（潘生丁）对实验性皮瓣存活的影响。在对照组中，皮瓣面积的39%存活。术前4小时开始每日两次腹腔注射4mg/kg双嘧达莫，使存活面积增加了18%。这一增加具有统计学意义（p<0.05）。存活情况的改善可能归因于该药物的血管舒张作用和/或该药物诱导的小血管增殖。
