Keene R J, Raphael M J
Calif Med. 1970 Sep;113(3):11-5.
Left ventricular aneurysm, interventricular septal defect and acute mitral valve incompetence due to papillary muscle damage are three mechanical complications which cause intractable heart failure following myocardial infarction. In each case surgical intervention can result in dramatic improvement of congestive heart failure.A hemodynamically significant left ventricular aneurysm enlarges the cardiac silhouette and frequently causes a localized protrusion as seen radiographically. Cardiac fluoroscopy will disclose an abnormal pulsation of the left ventricular border. The left ventricular angiogram establishes the diagnosis, reveals the extent of the aneurysm and may disclose a filling defect in the aneurysmal sac due to the presence of mural thrombus. Coronary arteriography shows occlusion of a major vessel, most commonly the anterior descending branch of the left coronary artery. Ischemic perforation of the interventricular septum and acute mitral incompetence due to severe papillary muscle damage both cause severe heart failure shortly after myocardial infarction. A similar pansystolic murmur accompanies both conditions, and differentiation between the two is rarely possible on the basis of the electrocardiogram or x-ray film of the chest. Ventricular cardiac catheterization and left ventricular angiocardiography are required for a correct diagnosis.
左心室室壁瘤、室间隔缺损以及因乳头肌损伤导致的急性二尖瓣关闭不全是心肌梗死后引发顽固性心力衰竭的三种机械性并发症。在每种情况下,手术干预都可显著改善充血性心力衰竭。具有血流动力学意义的左心室室壁瘤会使心脏轮廓增大,并常常导致X线检查可见的局部突出。心脏荧光透视检查会显示左心室边缘的异常搏动。左心室血管造影可确立诊断,显示室壁瘤的范围,并可能因壁内血栓的存在而显示室壁瘤囊内的充盈缺损。冠状动脉造影显示主要血管闭塞,最常见的是左冠状动脉前降支。室间隔缺血性穿孔和因严重乳头肌损伤导致的急性二尖瓣关闭不全都会在心肌梗死后不久引起严重心力衰竭。两种情况都会伴有类似的全收缩期杂音,仅凭心电图或胸部X线片很少能区分两者。正确诊断需要进行心室心导管检查和左心室心血管造影。