Ambrose S S, Parrott T S, Woodard J R, Campbell W G
Trans Am Assoc Genitourin Surg. 1979;71:144-5.
Of 63 patients with reflux and renal atrophy renal dysplasia was found in 9.5%. Pyelonephritis was apparent in 81% of the atrophic lesions. Urinary obstruction or ectasia was apparent in each case with dysplasia and only 2 were associated with histologic evidence of pyelonephritis. Pyelonephritis appears to be a major causal factor in atrophy occurring in renal units with reflux. Early urinary tract obstruction or distension may predispose to renal dysplasia.
在63例患有反流和肾萎缩的患者中，发现9.5%存在肾发育不全。81%的萎缩性病变表现为肾盂肾炎。在每例发育不全的病例中均可见尿路梗阻或扩张，且仅2例伴有肾盂肾炎的组织学证据。肾盂肾炎似乎是反流性肾单位萎缩的主要病因。早期尿路梗阻或扩张可能易导致肾发育不全。
