[Effect of high doses of the toxins from Bacillus thuringiensis strains on mice and sheep].

The investigation on Bac. thuringiensis toxines applied orally and subcutaneously on experimental white mice and on sheep proved that high doses of the dipel endotoxin are most toxic for mice of all strains (No. 862, 2E, 171) and spores and crystals of strain ND-1 used in dipel injection. The endotoxin of strain 862 applied orally to sheep at a dose of 10 cm3/kg body weight caused slight changes only to some paraclinical indices, namely: total protein, carotene, etc. Exotoxin had none or only slight toxic effect. The remaining strains applied to high doses proved almost harmless to mice.