人胎儿肝脏中缺乏胱硫醚酶：胱氨酸是必需的吗？
Absence of cystathionase in human fetal liver: is cystine essential?
作者信息
Sturman J A, Gaull G, Raiha N C
出版信息
Science. 1970 Jul 3;169(3940):74-6. doi: 10.1126/science.169.3940.74.
PMID:5465366
Abstract
Cystathionase activity is not measurable in the livers of 24 human fetuses and 3 premature infants, and the concentration of cystathionine in the liver is higher than that of the brain. The placenta does not subserve the trans-sulfuration function. Cystine (or cysteine) thus may be an essential amino acid in the immature human.
摘要
在24例人类胎儿和3例早产儿的肝脏中无法检测到胱硫醚酶活性，且肝脏中胱硫醚的浓度高于大脑。胎盘不具备转硫功能。因此，胱氨酸（或半胱氨酸）可能是未成熟人类的必需氨基酸。
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