Parent R A
Drug Chem Toxicol. 1979;2(3):295-307. doi: 10.3109/01480547908998250.
A poly(dimethylsiloxane) type silicone oil containing gamma-mercaptopropyl groups was evaluated for acute toxicity. Acute inhalation, oral and dermal toxicity, primary skin irritation, skin sensitization, eye irritation and human patch testing studies failed to demonstrate any significant response to this functional oil. Transient eye irritation and barely perceptible skin irritation were among the observations. On the basis of the data presented, it is doubtful that any problems of acute toxicity will result from the use of this silicone oil.
对一种含有γ-巯丙基的聚二甲基硅氧烷型硅油进行了急性毒性评估。急性吸入、口服和皮肤毒性、原发性皮肤刺激性、皮肤致敏性、眼睛刺激性及人体斑贴试验研究均未显示出对这种功能性硅油有任何显著反应。观察到的情况包括短暂的眼睛刺激和几乎难以察觉的皮肤刺激。根据所提供的数据，使用这种硅油是否会导致任何急性毒性问题值得怀疑。
