Appel W
J Clin Chem Clin Biochem. 1979 Dec;17(12):803-4.
The catalytic concentrations of lipase and carboxypeptidase A in sera of patients with and without pancreatic diseases show no correlation. 40 sera out of 44 with elevated values for lipase, derived from a collective of 135 different sera, showed no increase in the catalytic concentrations of carboxypeptidase A. The demanding titrimetric determination of lipase cannot be replaced by the more simple colorimetric determination of carboxypeptidase A for the laboratory diagnosis of pancreatic diseases.
患有和未患胰腺疾病患者血清中脂肪酶和羧肽酶A的催化浓度无相关性。在135份不同血清的样本中,44份脂肪酶值升高的血清中有40份,其羧肽酶A的催化浓度并未升高。对于胰腺疾病的实验室诊断,要求严格的脂肪酶滴定法测定不能被更简单的羧肽酶A比色法测定所取代。