Bornschein W
Leber Magen Darm. 1984 May;14(3):125-8.
Results of measurement of serum lipase activity as determined by a UV-test described by Myrick and a titrimetric assay as described by Rick were compared as far as sensitivity and specificity in diagnosis of pancreatitis is concerned. Sensitivity of the UV assay is low (45% falsely normal values), and specificity as well (falsely pathological values in 55.5% of patients with liver disease and 9% of normal persons). In the UV assay lipoproteinlipases are measured as well as hepatic esterases: in 17 samples from persons having received heparin lipase activity was increased 3-8 fold. In a total of 99 samples no correlation was found between the results of the 2 assays. As a consequence it can be stated that the UV-test as described by Myrick has no relevance in diagnosis of pancreatitis; the commercially available assay kit is withdrawn in the meantime.
就胰腺炎诊断的敏感性和特异性而言,对通过Myrick描述的紫外检测法测定的血清脂肪酶活性结果与Rick描述的滴定法测定结果进行了比较。紫外检测法的敏感性较低(45%的结果为假正常),特异性也较低(55.5%的肝病患者和9%的正常人结果为假病理)。在紫外检测法中,脂蛋白脂肪酶和肝酯酶都被检测:在17份来自接受肝素治疗者的样本中,脂肪酶活性增加了3至8倍。在总共99份样本中,两种检测结果之间未发现相关性。因此可以说,Myrick描述的紫外检测法与胰腺炎诊断无关;同时,该商业可用的检测试剂盒已被撤回。