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大鼠游泳训练引起的营养、心脏及肾上腺素能变化(作者译)

[Nutritional, cardiac and adrenergic changes induced by swimming training in rats (author's transl)].

作者信息

Moreau D, Guilland J C, Noirot P, Malval M

出版信息

J Physiol (Paris). 1979;75(7):755-64.

PMID:547071
Abstract

The effects of training were investigated in male Sprague Dawley rats group (N), fed ad libitum, by measuring the weight increase and food intake of the animals, biochemical parameters (myocardial triglycerides and glycogen levels), mechanical and metabolic properties of the heart, and adrenergic reactions to swimming stress. An other group of rats remaining sedentary served as control (T). Conditioned rats had been submitted to a one hour test swim 6 days a week for 9 weeks. Gradually additional weights were fixed to the thorax. At the end of training, the load reached 6% of the body weight. Both groups were sacrified by decapitation at the same time, thirty hours after the last swimming session. The study of mechanical performances and metabolic properties was achieved with isolated working heart preparation. Adrenergic reactions of swimming stress were evaluated from plasma, heart and adrenal catecholamine concentrations.

摘要

通过测量随意进食的雄性斯普拉格-道利大鼠组(N)动物的体重增加、食物摄入量、生化参数(心肌甘油三酯和糖原水平)、心脏的机械和代谢特性以及对游泳应激的肾上腺素能反应,研究训练的效果。另一组保持久坐的大鼠作为对照(T)。条件大鼠每周6天进行1小时的测试游泳,持续9周。逐渐在胸部固定额外的重量。训练结束时,负荷达到体重的6%。在最后一次游泳训练30小时后,两组大鼠同时断头处死。通过离体工作心脏标本研究机械性能和代谢特性。从血浆、心脏和肾上腺儿茶酚胺浓度评估游泳应激的肾上腺素能反应。

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