可溶性HL-A7抗原：在人血清β-脂蛋白组分中的定位。
Soluble HL-A7 antigen: localization in the beta-lipoprotein fraction of human serum.
作者信息
Charlton R K, Zmijewski C M
出版信息
Science. 1970 Nov 6;170(3958):636-7. doi: 10.1126/science.170.3958.636.
PMID:5470720
Abstract
The HL-A7 antigen of human leukocytes occurs as a soluble, low-density lipoprotein in the serum of HL-A7-positive individuals. Its presence in high concentration may inhibit direct leukocyte grouping, leading to erroneous results. This finding affords an easy method for the preparation of monospecific cytotoxic antiserums by absorption with serum fractions rather than leukocytes.
摘要
人类白细胞的HL-A7抗原在HL-A7阳性个体的血清中以可溶性低密度脂蛋白的形式存在。其高浓度存在可能会抑制直接白细胞分组，导致错误结果。这一发现为通过用血清组分而非白细胞吸收来制备单特异性细胞毒性抗血清提供了一种简便方法。
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