Wilson K S, Nyssen J, Alexander S
Med Pediatr Oncol. 1979;7(4):361-4. doi: 10.1002/mpo.2950070411.
A 39-year-old man had pain and swelling of the terminal phalanx of a finger. Radiograph was interpreted as osteomyelitis, and amputation through the mid-phalanx was performed. Histology revealed Ewing sarcoma. Lung metastases rapidly developed. Right lung irradiation and systemic chemotherapy, including doxorubicin, were instituted. He developed progressive severe right ventricular failure which was attributed to effects of large pulmonary metastases. Autopsy showed massive right ventricular metastases, the primary pathological cause of the heart failure, without evidence of doxorubicin cardiomyopathy.
一名39岁男性手指末节指骨出现疼痛和肿胀。X线片被诊断为骨髓炎，遂行经中节指骨截肢术。组织学检查显示为尤因肉瘤。很快出现了肺转移。开始进行右肺放疗及包括阿霉素在内的全身化疗。他出现了进行性严重右心室衰竭，这归因于巨大肺转移灶的影响。尸检显示右心室有大量转移灶，这是心力衰竭的主要病理原因，未发现阿霉素性心肌病的证据。
