Raafat J, Brown J A, Oster M W
Med Pediatr Oncol. 1978;5(1):51-4. doi: 10.1002/mpo.2950050107.
A 20-year-old man with metastatic Ewing Sarcoma developed severe congestive heart failure. Because he had been treated with a large amount of Adriamycin, the diagnosis was initially thought to be Adriamycin cardiotoxicity. However, ante- and post-mortem studies revealed the presence of massive cardiac metastases. At post-mortem, there was no evidence of Adriamycin cardiotoxicity. This case emphasizes that cardiac metastases must be considered in the differential diagnosis of heart failure in patients treated with Adriamycin.
一名患有转移性尤因肉瘤的20岁男性出现了严重的充血性心力衰竭。由于他此前接受了大量阿霉素治疗，最初诊断认为是阿霉素心脏毒性。然而，生前和死后研究均显示存在大量心脏转移瘤。尸检时，未发现阿霉素心脏毒性的证据。该病例强调，在接受阿霉素治疗的患者出现心力衰竭的鉴别诊断中，必须考虑心脏转移瘤。
