Kleinhans E, Berger H, Büll U, Moser E
Nuklearmedizin. 1979 Dec;18(5):232-6.
The diagnostic value of brain perfusion studies with radionuclides is based upon the careful determination of intracerebral vascular supply areas in sequential scintigraphic frames. This paper describes an automatic algorithm to determine cerebral hemisphere-borderlines (Regions of Interest). In 134 randomized brain perfusion studies, regions of interest were set by three techniques: automatically by a computer program at the beginning of the venous phase, automatically by using all images derived from the total bolus passage (40 sec.), and manual marking with a light pen at the beginning of the venous phase. A good correlation of these different techniques was obtained (r = 0.87). Furthermore, we found the bilateral perfusion index independent within a wide range, from the size of the marked regions and the quality of the injected indicator bolus. Time saving and lesser carefulness, concomitant with higher precision and reliability, in addition to the standardisation of the marking technique increase the diagnostic value of cerebral radionuclide angiography.
放射性核素脑灌注研究的诊断价值基于在连续闪烁图像中对脑内血管供应区域的仔细确定。本文描述了一种用于确定大脑半球边界线(感兴趣区域)的自动算法。在134项随机脑灌注研究中,通过三种技术设置感兴趣区域:在静脉期开始时由计算机程序自动设置、使用来自整个团注通过(40秒)的所有图像自动设置,以及在静脉期开始时用轻笔手动标记。这些不同技术之间具有良好的相关性(r = 0.87)。此外,我们发现双侧灌注指数在很宽的范围内独立于标记区域的大小和注入示踪剂团注的质量。节省时间和降低操作时的细致程度,同时具有更高的精度和可靠性,除了标记技术的标准化之外,还提高了脑放射性核素血管造影的诊断价值。