[Effectiveness of computer-assisted methods of evaluation of serial cerebral scintigrams (radionuclide angiography) (author's transl)].

A validation was made of various published methods of computer processing of radionuclide angiography studies of the brain: qualitative and quantitative evaluation of count-rate curves from regular and irregular regions of interest, evaluation of images of the arterial, capillary and venous phase of the tracer transit and the evaluation of function images of the slope, the height of the maximum and the time of the maximum of the regional countrate curves. By logical combination of results from various methods, an attempt was made to improve the final diagnosis in terms of higher sensitivity and simultaneously higher overall accuracy. It was found that the logical "OR" combination of slope function images, qualitative comparison of curves from irregular ROIs and quotient of the maxima of these curves is an "acceptable" processing method for clinicians with average experience in nuclear medicine. This was demonstrated by a comparison of ROC curves.