Berdel W, Berdel W E
Z Erkr Atmungsorgane. 1979 May;153(2):189-93.
Treatment of sarcoidosis by subcutaneous injections of a mixture of old tuberculin and blood of a highly tuberculin sensitive donor of an appropriate bloodgroup and by additional vaccination with BCG is described. All patients exhibiting x-ray stage I of the disease were cured without any relapse. The evaluation of these results as being due to our therapy is difficult, because of high frequency of spontaneous healing, however, during our treatment of the patients we never observed a progression of this stage into a more severe one. Of 60 patients exhibiting sarcoidosis of x-ray stage II and III treated by us, 54 were cured within an average time of therapy of 28 months as judged by clinical and x-ray parameters including 8 cases with sarcoidosis stage III, who at the end of the therapy showed only some residual scars, 5 of the 6 patients who did not respond to the therapy, had been unsuccessfully treated with corticosteroids before, or suffered from concomitant disease like extrinsic allergic alveolitis. In contrast to other methods of treating sarcoidosis, during our therapy we did not observe any harmful side effects.
描述了通过皮下注射旧结核菌素与血型合适且对结核菌素高度敏感的供体血液的混合物以及额外接种卡介苗来治疗结节病。所有疾病处于X线I期的患者均治愈且无任何复发。由于自愈频率较高，很难将这些结果归因于我们的治疗方法，然而，在我们治疗患者的过程中，从未观察到该阶段进展为更严重的阶段。在我们治疗的60例X线II期和III期结节病患者中，根据临床和X线参数判断，54例在平均28个月的治疗时间内治愈，其中包括8例III期结节病患者，在治疗结束时仅留下一些残余瘢痕，6例对治疗无反应的患者中，5例之前使用皮质类固醇治疗失败，或患有诸如外源性过敏性肺泡炎等伴发疾病。与其他治疗结节病的方法相比，在我们的治疗过程中未观察到任何有害副作用。
