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子宫颈癌相关泌尿系统并发症的防治进展。第三次通讯:上尿路功能障碍的肾图表现(作者译)

[Progress in prevention and control of urological complications associated with carcinoma of the cervix. Third communication: Renographic representation of functional disorders of the upper urinary tract (author's transl)].

作者信息

Lamm D, Fischer W

出版信息

Zentralbl Gynakol. 1979;101(22):1472-9.

PMID:547599
Abstract

Reported in this paper is the use of isotope nephrography in longitudinal examinations of 151 patients with cervix carcinoma who had undergone radical abdominal or vaginal surgery in the Gynaecological Hospital of Charité Berlin, between 1971 and 1973. Also included were 140 patients whose carcinoma treatment dated back nine to 15 years. While functional disturbances of the upper urinary tract within the five-year follow-up period dropped continuously from about 29 to five per cent in recent time, persisting disorders of secretion and/or ureteral dynamics recorded in ING checks from 16.4 per cent of earlier carcinoma treatments. The number of pathological isotope nephrograms recorded presurgically from patients who eventually died of recurrent carcinoma had been five times as high (49 per cent) as that recorded from cured patients. Only to some extent had those findings been attributable to the given carcinoma stage. Routine ING (isotope nephrography) also helped to identify nine cases of carcinoma recurrence, and its systematic use facilitated just as many decisions on fistulation of the functionally better kidney in cases of imminent anuria (uraemia). Yet, as a whole voiding disorders of the upper urinary tracts have decreased in the authors' hospital, as compared to records in the past. That improved situations is attributed to progress in carcinoma therapy but even more to energetic early action against urinary tract infections and postsurgical impairment of bladder voiding as well as to high-continuity monitoring of renal and ureteral functions. ING, today, deserves a firm position in all after-care programmes following treatment of cervical carcinoma.

摘要

本文报道了1971年至1973年间在柏林夏里特医院妇科接受根治性腹部或阴道手术的151例宫颈癌患者的同位素肾图纵向检查情况。还纳入了140例癌症治疗时间可追溯至9至15年前的患者。虽然在最近的五年随访期内,上尿路功能障碍从约29%持续下降至5%,但在早期癌症治疗的同位素肾图检查中记录到的持续分泌和/或输尿管动力学紊乱为16.4%。最终死于复发性癌症的患者术前记录的病理性同位素肾图数量是治愈患者的五倍(49%)。这些发现仅在一定程度上归因于给定的癌症分期。常规同位素肾图(ING)还有助于识别9例癌症复发情况,并且在即将出现无尿(尿毒症)的情况下,系统地使用该检查有助于就功能较好的肾脏进行造瘘做出同样多的决策。然而,与过去的记录相比,作者所在医院上尿路的排尿障碍总体上有所减少。这种改善归因于癌症治疗的进展,但更归因于对尿路感染和术后膀胱排尿障碍采取的积极早期措施,以及对肾脏和输尿管功能的高连续性监测。如今,同位素肾图在宫颈癌治疗后的所有随访计划中都应占有稳固的地位。

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