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正常受试者与尿毒症受试者血小板功能测试之间的关系。

Relationships between platelet function tests in normal and uraemic subjects.

作者信息

Hassanein A A, McNicol G P, Douglas A S

出版信息

J Clin Pathol. 1970 Jul;23(5):402-6. doi: 10.1136/jcp.23.5.402.

DOI:10.1136/jcp.23.5.402
PMID:5476867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476780/
Abstract

IN TESTS OF PLATELET FUNCTION IN NORMAL SUBJECTS, THE FOLLOWING RELATIONSHIPS WERE FOUND: the greater the platelet adhesiveness the less the ability to disaggregate after challenge with adenosine diphosphate (ADP), and the greater the disaggregation after ADP, the longer the clotting time in the test for platelet factor 3 availability. Such correlations were disturbed in uraemic patients.

摘要

在对正常受试者的血小板功能测试中，发现了以下关系：血小板黏附性越强，用二磷酸腺苷（ADP）激发后解聚的能力就越弱；ADP激发后解聚能力越强，血小板第3因子有效性测试中的凝血时间就越长。此类相关性在尿毒症患者中受到干扰。

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Relationships between platelet function tests in normal and uraemic subjects.正常受试者与尿毒症受试者血小板功能测试之间的关系。
J Clin Pathol. 1970 Jul;23(5):402-6. doi: 10.1136/jcp.23.5.402.
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Mathematical correlation between ADP-induced platelet aggregation and subsequent disaggregation. A parameter for the velocity of disaggregation.二磷酸腺苷（ADP）诱导的血小板聚集与随后解聚之间的数学关联。解聚速度的一个参数。
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3
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Effect of heparin and prostacyclin-heparin infusion on blood coagulation in haemodialysed patients.肝素和前列环素-肝素输注对血液透析患者血液凝固的影响。
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本文引用的文献

1
STUDIES ON PLATELET FACTOR-3 AVAILABILITY.血小板第3因子有效性的研究。
Br J Haematol. 1965 May;11:269-75. doi: 10.1111/j.1365-2141.1965.tb06587.x.
2
THE KAOLIN CLOTTING TIME OF PLATELET-RICH PLASMA: A TEST OF PLATELET FACTOR-3 AVAILABILITY.富含血小板血浆的高岭土凝血时间：血小板因子3可用性的检测
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Nature. 1961 Nov 11;192:531-2. doi: 10.1038/192531a0.
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Bleeding tendency in uremia.尿毒症中的出血倾向。
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Possible mechanism of aggregation of blood platelets by adenosine diphosphate.
Nature. 1966 Apr 9;210(5032):167-9. doi: 10.1038/210167a0.
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Platelet aggregation and the availability of platelet factor 3.
Br J Haematol. 1966 Nov;12(6):764-76. doi: 10.1111/j.1365-2141.1966.tb00164.x.